All seats and luggage room have been filled for the inaugural flight to Eritrea’s capital, Asmara.
A return ticket for the one-and-a -half-hour flight cost $800 (£600).
Our reporter who is among the lucky ones on board has snapped these pictures:
Complimentary champagne served on board
Champagne and selfies aboard first commercial flight in a generation between Ethiopia and Eritrea. Demand so great that Ethiopian Airlines scheduled a 2nd flight that took off just 15 mins later.
Ethiopian Airlines has shared a picture of its first passenger flight – after 20 years – leaving for a journey to Eritrea.
News site Addis Standard reported 456 passengers are on board.
More photos below: